Poster Presentation on Precision Granulation™

A description of the work on Precision Granulation™ done by Niro Pharma Systems and the Department of Pharmacy of the National University of Singapore and presented at the November 2002 AAPS Poster Session in Toronto.

The work on Precision Granulation™ as an Alternative Granulation Method was completed by following people -

• Celine Liew representing Niro Pharma Technologies, Niro Inc. and Department of Pharmacy, National University of Singapore
• Kim Walter from Niro Pharma Systems, Niro Inc.
• Anthony Wigmore from Niro Pharma Systems, Aeromatic-Fielder Limited
• Albert Brzecko fromNiro Pharma Technologies, Niro Inc.
• Paul WS Heng from Department of Pharmacy, National University of Singapore.

Please click on the following link to download this poster presentation as a PDF file: description of work on Precision Granulation™ done by Niro Pharma Systems and the Department of Pharmacy of the National University of Singapore.

Please follow the links below in order for a detailed discussion of the work done on Precision Granulation™:

• Introduction
• Materials
• Part I - Methodology & Results
• Part II Methodology, Results, & Statistical Analysis
• Part III and Conclusion

Introduction

Fluid Bed Granulation and High Shear Granulation are presently the most important wet granulation techniques employed in the pharmaceutical industry (1). Precision Granulation™, a new bottom spray method, is evaluated for comparison with the conventional granulation methods (2).

High Volume Flow Granulation Liquid Low Volume Flow

The Precision Granulation™ process

Objectives

Materials