Precision Granulation™ - Materials

 Print     Send link
Home / GEA Pharma Systems / Poster Presentation on Precision Granulation™ / Precision Granulation™ - Materials
Table 1 Formulations used in the granulation studies
Study
Part 1
Part 2
Part 1
Part 1
Part 3
Material
Formulation A1 (%)
Formulation A2 (%)
Formulation B (%)
Formulation C (%)
Formulation D (%)
Lactose 200M* (Pharmatose 200M, DMV)
88
88
-
-
-
Lactose 450M* (Pharmatose 450M, DMV)
-
-
88
-
-
Powdered sugar
-
-
-
88
-
Acetaminophen (Mallinckrodt)
-
-
-
-
88
Povidone / Polyvinyl pyrrolidone (aKollidon 30, BASF; bPlasdone K29/32, ISP)
5a
5b
5a
5a
5b
Microcrystalline cellulose (Avicel PH-101, FMC)
5
5
5
5
5
Crospovidone (Polyplasdone XL10, ISP)
2
2
2
2
2

* From DMV product literature :

  • Lactose 200M - average particle size 0.040 mm; % <0.045 mm: 50-65
  • Lactose 450M - average particle size 0.020 mm; % <0.045 mm: minimum 90

 

Schematic diagrams of components of the Precision Granulator™
Schematic diagrams of components of the Precision Granulator™

 

MP-1™ with Precision Granulation™ module
MP-1™ with Precision Granulator™ module

 

Precision Granulation™ - Introduction

Part I - Methodology & Results

Request Information
If you are interested in learning more about a particular product and/or service offered by GEA Process Engineering Inc, please use this form to contact us,

Request more information Click here to request more information

 Back Top of page Top of page