Lyophilizer Applications

Lyophilized (freeze dried) products retain their original properties. By adding water or other solvents they can be reconstituted easily and very quickly to a usable solution. There is no need for cooling during storage, therefore storage costs decrease and handling is made easier.

Many pharmaceutical products are lyophilized (freeze dried) in vials.

GEA Lyophil cGMP compliant production lyophilizer (freeze dryer)

Lyophilized biological product

There is a wide range of substances for which freeze drying (lyophilization) is used as conservation/preservation method. In the aseptic pharmaceutical and biotechnology production, freeze drying, or lyophilization are often applied to the following products: antibiotics, bacteria, vaccines, hormones, vitamins, enzymes, ferments, peptides, liposomes, collagen, plant extracts, liver extracts, radio-immuno-essays, blood plasma, plasma fractions, and antibodies.

Commonly, water is used as solvent, but in some pharmaceutical applications alcohol is used to dissolve or disperse the product. In this case the lyophilizer design must comply with ATEX guidelines.

GEA Lyophil is able to support its customers in the installation and operation of a reliable, validated lyophilization process for pharmaceutical and biological products.