High Containment Technology

High Containment

Contamination control is vital in a wide range of manufacturing operations in the chemical and pharmaceutical industries, and above all, in powder, granulate and other bulk material handling processes. The most advanced containment solution today is the patented split-valve technology used by Niro Pharma Systems' Buck docking system.

Two Valves, One System

During the charging and discharging of production units with powders, granulates, and various other bulk materials, containment standards are very high. The Buck docking system consist of active and passive valves, which seal two containers. The active valve, operated manually or by an automated system, in mounted on the process station, while the passive valve is fitted on the mobile container. When docked, the two valves interlock for complete containment during product transfer.

Discharging & Dosing

The Buck discharge system, when integrated with the docking system, prevents bridging in the container for unrestricted product flow at a constant rate. Customized for the application, the disharge system is fitted between the container flange and the passive valve. As the container is filled, the product surface is leveled. A vibrating rod penetrating above the top fill level may be fitted to prevent a negative pressure buildup in the top part of the container.

The Buck dosing system controls the rate of discharge. It uses a weighing device for highly accurate container filling or emptying.

The discharge system can be easily retrofitted to existing systems.

Cleaning Systems

Feeding & Emptying

Agent manufacture is the first phase of the tablet production process. Contamination, occupational safety and health, quality management, cleaning, and FDA approval are all essential considerations in the design of equipment for this operation. Buck has retrofitted a number of centrifuges, paddle dryers, and double-cone dryers with Buck docking and discharge systems. Pilot installations at many manufacturing facilities demonstrate the easy integration of high-containment systems into fully automated manufacturing processes. Automatic docking and undocking allows the complete automation of the production system.

Pharma Charge Drums

Charge drums are essential links in the high-containment material handling chain. Buck has the right container for transporting and handling agents in small and very small batches. Applications range from laboratory and production uses to sampling in a high-containment environment. High-grade stainless steel and plastic single-use containers are the systems of choice for cost-effective material handling in a controlled environment.

Feed Weighing

Customized dispensing systems allow pharmaceutical manufacturers to optimize this vital operation in the production of solid dosage forms. The equipment features highly accurate raw material feed weighing for transfer to the mixer. It allows precise dosage of all materials to standards far beyond recognized pharmaceutical practice. Solid dosage from containers fitted with Buck docking systems offer dust-free transfer, container monitoring, and container check weighing. The systems satisfy all GMP and FDA standards and have been validated for all applications.

Hazardous Materials

Buck pharma UN container, pharma charge drums, and docking systems are designed for worldwide transportation of hazardous solid materials. Full-size and laboratory-size containers equipped with the Buck docking system are filled, transported, and emptied easily wherever transportation needs arise. Material transfer operations become unnecessary. The container is filled once and emptied once in a high-containment pressurized environment, eliminating all contamination risks. Systems are certified under UN Code 11A/X. Buck's wide range of sizes ensures that we have the right equipment for any application.