Fluid Bed Top Spray Granulation

Granulation can be performed using fluid beds fitted with spray nozzles. During the last 10 years, fluid beds have improved dramatically in response to single pot technology competition. It is possible to have completely closed material handling by a closed linking with upstream and downstream equipment (Figure 2). Also, fully automatic cleaning (cleaning-in- place [CIP] and wash-in-place [WIP]) in fluid beds using stainless steel filters now compares favourably with what is possible in a single pot.

Figure 2 Fluid Bed Top Spray Granulation