New Swinging Bowl Feature in UltimaPro™ Range

Improved Granulate Quality By Use of Swinging Bowl

In view of the current trend in pharmaceutical industry to move towards increased containment, many old production processes need to be reviewed. The traditional 'open' processes of granulation in planetary mixers and drying in ovens are gradually replaced with more contained processes such as One-Pot processing. The drug formulations for such processes often contain only a small amount of binder or a weak binder, and produce weak granulations that are easily broken by mechanical action. In a standard One-Pot processor, the necessary action of the mixer arm during drying causes attrition of the granulate and the creation of fines, which may result in tabletting problems.

UltimaPro™ 10

The UltimaPro™ range by Collette NV now offers a solution to those problems by using a swinging bowl to move the product during drying. The swinging action of the bowl has 2 important effects during drying. First the product is brought into contact with the energy source for drying - the heated wall - without activating the mixer arm, thus without exerting mechanical stress on the product. Secondly, the contact surface between the product and the heated wall is increased, thus optimizing the energy transfer necessary for drying. Studies have shown a significant reduction in the amount of fines created after drying when a swinging bowl was used, thus improving the tabletting process. Also the drying time was significantly reduced when using the swinging bowl, which is an important economic aspect.

The UltimaPro™ of Collette NV, equipped with a swinging bowl, thus presents a solution for processing old, weak formulation in a modern, contained way.

Contact Information

North America:
Niro Inc.
Contact: H. McCoy Knight, National Sales Manager
Tel. : +1-410 997 7010
Fax : +1-410 997 5021
E-mail : mccoy.knight@geagroup.com

For inquiries outside North America:
Collette NV
Contact: Griet Van Vaerenbergh, Sales Engineer
Tel. : +32 3 350 12 11
Fax : +32 3 353 20 55
E-mail : griet.vanvaerenbergh@collette.be
Web: http://www.gea-ps.com/

GEA Pharma Systems is world leader in providing advanced processing solutions for solid dosage forms to the pharmaceutical industry. Based on a dedication to research and durable quality, GEA Pharma Systems offers a wide range of solutions, form individual pieces of equipment to complete integrated plants, by uniting the state-of-the-art technologies of Aeromatic, Buck, Collette, Courtoy, Fielder, Nica™ and Niro.